Granulomatous Lesions in Bone Marrow

RANULOMATOUS LESIONS have been found iii paraffin sections nlade from particles of bone marrow removed by aspiration from patients w’it-h tuberculosis, histoplasmosis, brucehlosis, sarcoidosis, infectious mononucleosis, malignant lymphomas or miscellaneous and indeterminate disorders.19 In a previous paper,4 I discussed the significance of granulomatous lesions foiits(l in sections made from bone marrow aspirated from 50 patients on whom such studies were made as an aid in diagnosis. The value of examinimig serial sections of all available particles of marrow’ was stressed. It is the purpose of this paper to discuss the significance of granulomatous lesions found in sections of bone marrow aspirated from an additional 100 patients on whom studies of marrow w’ere undertaken as an aid in establishing a diagnosis. The combined total of 150 cases w’ill be considered in the section on comment. and summary and in the final table. The sections preceding the comment. and summary will concern t-hensselves only with the presentgroup of 100 cases.